How semaglutide works
Semaglutide mimics GLP-1, a hormone your gut releases after eating. It slows stomach emptying, signals fullness to the brain and helps steady blood sugar, which for many people means smaller portions feel satisfying and cravings quiet down.
In the STEP 1 clinical trial, adults without diabetes taking semaglutide 2.4 mg weekly alongside lifestyle changes lost an average of about 15% of body weight over 68 weeks. Individual results vary.
Titration: starting low, increasing slowly
Doses typically begin low and increase in steps about every four weeks. This gives your digestive system time to adjust and lowers the chance of nausea. Your provider decides whether and when to step up based on how you feel and how you are progressing.
- Start at a low introductory dose
- Step up gradually only if tolerated
- Stay at the lowest dose that keeps you progressing
Medical monitoring at every stage
- Initial evaluation of health history, medications and goals
- Weight and progress check-ins at the clinic
- Review of side effects and dose adjustments
- Screening for situations where GLP-1 medications are not appropriate
Semaglutide pricing
Pay as you go, with no contracts or signup fees. Prices increase with dosage as the medication titrates up.
- Months 1 & 2: $155 / month
- Months 3 & 4: $300 / month
- Month 5 and beyond: $350 / month
Side-effect coaching
The most common side effects are gastrointestinal: nausea, constipation, reflux or loose stools, usually during dose increases. We coach patients on eating pace, hydration, protein and fiber so these stay manageable. See our GLP-1 side-effect pathway for details.